Academic Magnet (6-1, 1-1) at Battery Creek (3-4, 2-0), 7:30 p.m.
Last year: Academic Magnet won 28-20.
Last week: Academic Magnet lost 28-20 to Whale Branch; Battery Creek beat North Charleston 33-16.
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The skinny: "Daquan Dilbert must have a great game to help fill the shoes of his brother if he is unable to go 100 percent," Battery Creek head coach Jim Shuman said. "We must have a strong defensive performance to contain the Magnet running attack. Our special teams have continued to show great improvement, so they must sustain that. We've only been at home twice this season thus far, so we have to make sure we adjust to the new schedule to being at home."
Barnwell (5-3) at Ridgeland-Hardeeville (1-6, 0-2), 7:30 p.m.
Last year: Ridgeland-Hardeeville won 36-17.
Last week: Barnwell beat Woodland 52-21; Ridgeland-Hardeeville lost to Wade Hampton 41-6.
The skinny: "Show up! Play well from start to finish and everything in between."
That's what Jaguars head coach Jahmaal Nelson said his team has to do to win this week's non-region game.
"The young men choose to come out and play on their own, therefore they should be motivated intrinsically themselves. I just keep working them hard in practice and sticking to the task at hand, which is trying to prepare them to be productive in life. This is my philosophy regardless if we were undefeated or if we hadn't won a game."
Beaufort (4-3, 1-1) at Hanahan (5-2, 2-0), 7:30 p.m.
Last year: Hanahan won 24-14.
Last week: Beaufort lost 41-30 to Hilton Head Island; Hanahan beat Stall 56-14.
The skinny: "We really need a win. Going into that game last week, our kids didn't think they could lose," Beaufort head coach Mark Clifford said. "They were getting better. ... Losing a close game like it was, it was really like getting hit in the face. We've just got to be tough and go in there and play a football game. No tricky stuff. It's going to be blocking and tackling, and the team that does it better will come out on top."
Bluffton (5-3, 0-1) at Fort Dorchester (8-0), 7:30 p.m.
Last year: Fort Dorchester won 34-0.
Last week: Bluffton lost 53-28 to Ashley Ridge; Fort Dorchester beat Colleton County 44-6.
The skinny: Bluffton head coach Ken Cribb is happy with his team despite the loss to Ashley Ridge.
"We played extremely well until the wheels fell off, Cribb said. "(We) must play flawless to have a chance to win (this week). We plan on bringing our slingshots and a pocket of rocks. Goliath will be tough but is not unbeatable. We are fairly healthy, and the kids are having fun and enjoying the season and playing together. The turnovers sank the ship last week. No turnovers and Ashley Ridge would no longer be undefeated."
Charleston Collegiate (3-4, 3-2) at John Paul II (1-7, 1-5), 7:30 p.m.
Last year: First meeting.
Last week: Charleston Collegiate beat Ridge Christian 44-28; John Paul II lost 46-36 to Cathedral Academy.
The skinny: "We are progressing well, and feel like we will succeed in this week's game," Golden Warriors head coach Eric Notarus said. "We are at a place in our program where players are beginning to come into their own, and that is where we want our players to be. We have been struggling to develop football sense, and that hard work is beginning to pay off."
Curtis Baptist (3-5, 1-3) at Thomas Heyward Academy (5-4, 3-1), 7:30 p.m.
Last year: Curtis Baptist won 47-14.
Last week: Curtis Baptist lost 36-14 to Colleton Prep; Thomas Heyward Academy beat Hilton Head Christian 52-34.
The skinny: If the Rebels run the ball like they did last week (428 yards), they should move to 4-1 in the region.
Garrett (4-3, 0-2) at Whale Branch (3-4, 1-1), 7:30 p.m.
Last year: Whale Branch won 21-0.
Last week: Garrett lost 35-6 to Bishop England; Whale Branch beat Academic Magnet 28-20.
The skinny: "(Garrett is) very athletic and presents matchup problems for our secondary," Warriors head coach Jerry Hatcher said. "I'm expecting a close game. Ball security will be the key. We are starting to get players back. Amir Chisolm (out since Beaufort) has been cleared, Caleb Hill came back last week, and Donavan Whatley is cleared after missing one game."
Hilton Head Christian (2-5, 0-4) at St. Andrew's (2-6, 1-2), 7:30 p.m.
Last year: Hilton Head Christian won 24-14.
Last week: Hilton Head Christian lost 52-34 to Thomas Heyward Academy; St. Andrew's lost 28-20 to Hilton Head Prep.
The skinny: "St. Andrew's is solid. They are well-coached and play fundamentally sound," Eagles head coach Matt Smith said. "I'm impressed with their option game and their tackling. Our keys are to show improvement from last week and cut down on turnovers. We've given up too many turnovers for touchdowns. Two pick-sixes last week were too much to overcome. We are very young, and we continue to improve. Knowing we still have a long shot at playoffs is motivation enough."
Hilton Head Island (7-0, 2-0) at Orangeburg-Wilkinson (3-5, 1-1), 7:30 p.m.
Last year: Orangeburg-Wilkinson won 54-14.
Last week: Hilton Head Island beat Beaufort 41-30; Orangeburg-Wilkinson beat Berkely 20-14.
The skinny: "Don't let the record fool you," Seahawks head coach BJ Payne said. "(O-W is) by far the best team we have played this year. Their QB was out with a dislocated jaw up to this point, and they have by far the best defense we have played. They haven't given up more than 20 in any game."
Hilton Head Prep (5-3, 4-1) at Dorchester Academy (3-5, 1-2), 7:30 p.m.
Last year: Hilton Head Prep won 24-15.
Last week: Hilton Head Prep beat St. Andrew's 28-20; Dorchester Academy beat First Baptist 63-34.
The skinny: "(We) are very similar," Dolphins head coach Kevin Wald said of Dorchester Academy. "They have had some injuries to key players early in the season, including a very good quarterback and running back. They are both back now and they are playing well as they put up 60 points last week. We need to improve on ball security, as we had three lost fumbles last week that made the game closer than it needed to be. If we win tomorrow, we will win the region or no worse than second. If we lose we fall to third or possibly fourth."
Prep lineman Davis Puckey is lost for the season with a broken leg and senior Kyle Adkins is questionable.