Bluffton traveled to Georgia to play South Effingham on Friday night and came home with its first loss of the season as the Mustangs held off the Bobcats, 23-20.
"It was a good game," Bluffton coach Ken Cribb said. "Their staff did a great job preparing their team. We fought hard for four quarters and came up short."
The Mustangs scored on the opening play on a long double pass and the Bobcats (1-1) played from behind the rest of the night.
Bluffton scored its first points in the second quarter when Gerald Roberson capped a long drive with a short touchdown run to cut the South Effingham lead to 13-6.
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Roberson struck again, taking a kickoff back for a score late in the first half to pull Bluffton to within 20-12.
Another Bluffton touchdown pulled the Bobcats to within 23-20 late in the fourth quarter, but on their final drive, an interception sealed the Bobcats' fate.
"We sputtered," Cribb said of the Bobcats offense. "It's been a long night. We made some youthful mistakes and missed on some opportunities."