Jaron Blossomgame scored a season-high 27 points, four other Clemson players scored in double figures and the Tigers held off High Point 83-74 on Friday night.
Donte Grantham and Avry Holmes added 13 points each to help Clemson (3-2) end a two-game losing skid.
The Panthers (3-3) got 22 points from Andre Fox.
After coming up short against No. 9 Xavier and Oklahoma in last week’s Tire Pros Invitational, the Tigers shot 48 percent from the field and made 22 of their 24 free throws Friday.
Anthony Lindauer added 16 points for the Panthers, who trailed by as many as 16 in the second half.
High Point would get to within four points on Lindauer’s layup with 6:17 to play, but a jumper by Marcquise Reed and a steal and dunk by Blossomgame pushed Clemson’s lead back up to eight with 5:22 to play.
Clemson: Shelton Mitchell, who was expected to be the starting point guard before a Nov. 8 knee surgery to repair torn meniscus sidelined him, made his season debut off the bench Friday. The Vanderbilt transfer had two assists and no points on two shot attempts in 11 minutes of action.